Longevity & Cellular
Research overviews of mitochondrial and longevity-oriented compounds — NAD+, MOTS-c, epithalon, SS-31 (elamipretide), humanin, and glutathione — covering cellular mechanisms and the state of the preclinical evidence.
NMN vs. NR: Comparing Two NAD+ Precursors in Research
NMN and NR are two distinct NAD+ precursors that researchers have used to study cellular energy metabolism and longevity pathways. This overview compares their mechanisms, preclinical findings, and research profiles.
SS-31 (Elamipretide): A Research Overview of This Mitochondria-Targeting Peptide
SS-31 (elamipretide) is a cell-permeable tetrapeptide investigated for its ability to localize to the inner mitochondrial membrane and interact with cardiolipin. Preclinical research explores its potential role in models of oxidative stress, bioenergetic decline, and age-associated mitochondrial dysfunction.
MOTS-c: A Research Review of the Mitochondrial-Derived Peptide
MOTS-c is a short peptide encoded within the mitochondrial genome, and MOTS-c research has uncovered a range of intriguing metabolic and cellular mechanisms in preclinical models. This review summarizes what scientists currently understand.
What Is NAD+ and What Have Studies Revealed About This Coenzyme?
NAD+ is a coenzyme central to cellular energy metabolism and DNA repair. Here is a research-focused overview of what studies have revealed about its biology and potential roles.
Mitochondrial Peptides: An Overview of the Research on MOTS-c, Humanin, and SS-31
Mitochondrial peptides are a class of small signaling molecules encoded within the mitochondrial genome. Preclinical research has investigated their roles in cellular energy regulation, stress response, and metabolic signaling.
Humanin: A Review of Mitochondrial-Derived Peptide Research
Humanin is a small mitochondrial-derived peptide that has attracted growing interest in longevity research. This overview examines what preclinical studies have uncovered about its mechanisms and areas of investigation.
Glutathione: A Research Review of the Body's Master Antioxidant
Glutathione is a tripeptide that has attracted significant scientific interest for its role in cellular redox balance and oxidative stress defense. This review summarizes key preclinical findings from laboratory research.
Epithalon: A Review of Telomere and Longevity Research
Epithalon is a synthetic tetrapeptide investigated in preclinical models for its proposed influence on telomerase activity, telomere length, and aging-related cellular processes. This overview surveys the published research landscape.